My Bibliography

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Senfeld J, Peng Q, Shi Y, Qian S, Shen J. A Purinergic Mechanism Underlying Metformin Regulation of Hyperglycemia. [preprint]. 2022 September. Available from: https://doi.org/10.1101/2022.09.27.509754.

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Lucas LM, Dwivedi V, Senfeld JI, Cullum RL, Mill CP, Piazza JT, Bryant IN, Cook LJ, Miller ST, Lott JH 4th, Kelley CM, Knerr EL, Markham JA, Kaufmann DP, Jacobi MA, Shen J, Riese DJ 2nd. The Yin and Yang of ERBB4: Tumor Suppressor and Oncoprotein. Pharmacol Rev. 2022 Jan;74(1):18-47. doi: 10.1124/pharmrev.121.000381. Review. PubMed PMID: 34987087.

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Peng Q, Qian S, Alqahtani S, Panizzi P, Shen J. The P2Y2 Nucleotide Receptor Mediates Monocyte Tissue Factor Expression and Endotoxemia Death in Mice. [preprint]. 2021 December. Available from: https://doi.org/10.1101/2021.12.28.474395.

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Peng Q, Alqahtani S, Nasrullah MZA, Shen J. Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells. Eur J Pharmacol. 2021 Jan 15;891:173706. doi: 10.1016/j.ejphar.2020.173706. Epub 2020 Nov 3. PubMed PMID: 33152337; PubMed Central PMCID: PMC7770062.

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Shi Y, Riese DJ 2nd, Shen J. The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer. Front Pharmacol. 2020;11:574667. doi: 10.3389/fphar.2020.574667. eCollection 2020. Review. PubMed PMID: 33363463; PubMed Central PMCID: PMC7753359.

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Alhowail A, Zhang LX, Buabeid M, Shen JZ, Suppiramaniam V. Role of the purinergic P2Y2 receptor in hippocampal function in mice. Eur Rev Med Pharmacol Sci. 2020 Nov;24(22):11858-11864. doi: 10.26355/eurrev_202011_23843. PubMed PMID: 33275273; PubMed Central PMCID: PMC10015965.

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Peng Q, Alqahtani S, Nasrullah MZ, Shen J. Functional Evidence for Biased Inhibition of G protein Signaling by YM-254890 in Human Coronary Artery Endothelial Cells. bioRxiv : the preprint server for biology. 2020 August.

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Peng Q, Shen J. The P2Y2 Nucleotide Receptor Mediates Tissue Factor Expression in Human Monocytes. The FASEB Journal. 2020 April; 34(S1):1-1.

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Senfeld JI, Shen J. Evidence for P2Y2 Receptor Facilitation of Hyperglycemia‐induced Insulin Resistance in Human Hepatocytes. The FASEB Journal. 2020 April; 34(S1):1-1.

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Nasrullah MZ, Peng Q, Shen J. The P2Y2 Receptor Mediates Hyperglycemia-induced Insulin Resistance in Human Skeletal Muscle Cells. The FASEB Journal. 2019 April; 33(1_supplement):514.3-514.3.

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Peng Q, Shen J. YM-254890 is a General Inhibitor of G Proteins. The FASEB Journal. 2019 April; 33(1_supplement):503.7-503.7.

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Li H, Zhao Z, Ling J, Pan L, Zhao X, Zhu H, Yu J, Xie B, Shen J, Chen W. USP14 promotes K63-linked RIG-I deubiquitination and suppresses antiviral immune responses. Eur J Immunol. 2019 Jan;49(1):42-53. doi: 10.1002/eji.201847603. Epub 2018 Nov 28. PubMed PMID: 30466171.

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Wang C, Chen W, Shen J. CXCR7 Targeting and Its Major Disease Relevance. Front Pharmacol. 2018;9:641. doi: 10.3389/fphar.2018.00641. eCollection 2018. Review. PubMed PMID: 29977203; PubMed Central PMCID: PMC6021539.

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Zhao X, Pu D, Zhao Z, Zhu H, Li H, Shen Y, Zhang X, Zhang R, Shen J, Xiao W, Chen W. Teuvincenone F Suppresses LPS-Induced Inflammation and NLRP3 Inflammasome Activation by Attenuating NEMO Ubiquitination. Front Pharmacol. 2017;8:565. doi: 10.3389/fphar.2017.00565. eCollection 2017. PubMed PMID: 28878677; PubMed Central PMCID: PMC5572209.

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Liu Y, Zhang L, Wang C, Roy S, Shen J. Purinergic P2Y2 Receptor Control of Tissue Factor Transcription in Human Coronary Artery Endothelial Cells: NEW AP-1 TRANSCRIPTION FACTOR SITE AND NEGATIVE REGULATOR. J Biol Chem. 2016 Jan 22;291(4):1553-1563. doi: 10.1074/jbc.M115.681163. Epub 2015 Dec 2. PubMed PMID: 26631725; PubMed Central PMCID: PMC4722438.

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Ma W, Liu Y, Wang C, Zhang L, Crocker L, Shen J. Atorvastatin inhibits CXCR7 induction to reduce macrophage migration. Biochem Pharmacol. 2014 May 1;89(1):99-108. doi: 10.1016/j.bcp.2014.02.014. Epub 2014 Feb 28. PubMed PMID: 24582769.

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Shen J, Ma W. SDF-1: a Cell Mobilizer as a Stabilizer for Atherosclerosis?. Arterioscler Thromb Vasc Biol. 2013 June; eLetter(60).

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Ma W, Liu Y, Ellison N, Shen J. Induction of C-X-C chemokine receptor type 7 (CXCR7) switches stromal cell-derived factor-1 (SDF-1) signaling and phagocytic activity in macrophages linked to atherosclerosis. J Biol Chem. 2013 May 31;288(22):15481-94. doi: 10.1074/jbc.M112.445510. Epub 2013 Apr 18. PubMed PMID: 23599431; PubMed Central PMCID: PMC3668710.

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Shen J, Ma W, Liu Y. Deacetylase SIRT6 deaccelerates endothelial senescence. Cardiovasc Res. 2013 Mar 1;97(3):391-2. doi: 10.1093/cvr/cvs421. Epub 2012 Dec 19. PubMed PMID: 23257021.

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Ding L, Ma W, Littmann T, Camp R, Shen J. The P2Y(2) nucleotide receptor mediates tissue factor expression in human coronary artery endothelial cells. J Biol Chem. 2011 Jul 29;286(30):27027-38. doi: 10.1074/jbc.M111.235176. Epub 2011 Jun 7. PubMed PMID: 21652710; PubMed Central PMCID: PMC3143661.

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Shen J, Chandrasekharan UM, Ashraf MZ, Long E, Morton RE, Liu Y, Smith JD, DiCorleto PE. Lack of mitogen-activated protein kinase phosphatase-1 protects ApoE-null mice against atherosclerosis. Circ Res. 2010 Mar 19;106(5):902-10. doi: 10.1161/CIRCRESAHA.109.198069. Epub 2010 Jan 21. PubMed PMID: 20093631; PubMed Central PMCID: PMC2847792.

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Kinney CM, Chandrasekharan UM, Yang L, Shen J, Kinter M, McDermott MS, DiCorleto PE. Histone H3 as a novel substrate for MAP kinase phosphatase-1. Am J Physiol Cell Physiol. 2009 Feb;296(2):C242-9. doi: 10.1152/ajpcell.00492.2008. Epub 2008 Nov 19. PubMed PMID: 19020052; PubMed Central PMCID: PMC2643854.

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Shen J, DiCorleto PE. ADP stimulates human endothelial cell migration via P2Y1 nucleotide receptor-mediated mitogen-activated protein kinase pathways. Circ Res. 2008 Feb 29;102(4):448-56. doi: 10.1161/CIRCRESAHA.107.165795. Epub 2008 Jan 3. PubMed PMID: 18174464.

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Shen J, DiCorleto PE. Adenosine prompts the heart to recruit endothelial progenitors. Circ Res. 2008 Feb 15;102(3):280-2. doi: 10.1161/CIRCRESAHA.107.170522. PubMed PMID: 18276925.

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Shen J, Halenda SP, Sturek M, Wilden PA. Cell-signaling evidence for adenosine stimulation of coronary smooth muscle proliferation via the A1 adenosine receptor. Circ Res. 2005 Sep 16;97(6):574-82. doi: 10.1161/01.RES.0000181159.83588.4b. Epub 2005 Aug 11. PubMed PMID: 16100051.

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Shen J, Halenda SP, Sturek M, Wilden PA. Novel mitogenic effect of adenosine on coronary artery smooth muscle cells: role for the A1 adenosine receptor. Circ Res. 2005 May 13;96(9):982-90. doi: 10.1161/01.RES.0000165800.81876.52. Epub 2005 Apr 14. PubMed PMID: 15831818.

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Shen J, Seye CI, Wang M, Weisman GA, Wilden PA, Sturek M. Cloning, up-regulation, and mitogenic role of porcine P2Y2 receptor in coronary artery smooth muscle cells. Mol Pharmacol. 2004 Nov;66(5):1265-74. doi: 10.1124/mol.104.002642. Epub 2004 Jul 27. PubMed PMID: 15280443.

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Shen JZ, Zheng XF, Wei EQ, Kwan CY. Green tea catechins evoke a phasic contraction in rat aorta via H2O2-mediated multiple-signalling pathways. Clin Exp Pharmacol Physiol. 2003 Jan-Feb;30(1-2):88-95. doi: 10.1046/j.1440-1681.2003.03796.x. PubMed PMID: 12542460.

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Zhang Y, Shen J, Lu Y. Role of EGF receptor in H2O2-induced contraction of rat aorta. Zhejiang Medicine. 2002 July; 24(7):407-409.

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Yan L, Wei E, Shen J. Protection by haloperidol against N-methyl--D-aspartate-induced injury of rat primary hippocampal neuronal cultures. Bulletin of Science and Technology. 2002 April; 18(4):265-269.

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Yan LQ, Wei EQ, Hu HT, Zhang WP, Wang ML, Shen JZ. [Novel quantitative method for evaluating oxygen/glucose deprivation-induced injury of hippocampal slices]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002 Apr;31(2):81-85. doi: 10.3785/j.issn.1008-9292.2002.02.005. PubMed PMID: 12539266.

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Yan L, Wei E, Shen J, Shen B. Protective effect of haloperidol on oxygen/glucose deprivation- and NMDA-induced injuries on rat hippocampal slices and primary neurons. Acta Pharmaceutica Sinica. 2002 March; 37(12):922-926.

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Kang H, Wei EQ, Yang XH, Zhang WP, Shen JZ. VCAM-1 expression, eosinophil infiltration, and pharmacological modulation in rat allergic airway inflammation. Acta Pharmacol Sin. 2002 Feb;23(2):157-61. PubMed PMID: 11866877.

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Wei EQ, Shen JZ. [Trends in the post-genomic pharmacological research]. Sheng Li Ke Xue Jin Zhan. 2002 Jan;33(1):7-11. Review. PubMed PMID: 12001739.

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Shen JZ, Zheng XF, Wei EQ, Kwan CY. Evidence against inhibition of sarcoplasmic reticulum Ca2+-pump as mechanism of H2O2-induced contraction of rat aorta. Acta Pharmacol Sin. 2001 Jun;22(6):498-504. PubMed PMID: 11747754.

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Shen JZ, Zheng XF, Kwan CY. Evidence for P(2)-purinoceptors contribution in H(2)O(2)-induced contraction of rat aorta in the absence of endothelium. Cardiovasc Res. 2000 Aug 18;47(3):574-85. doi: 10.1016/s0008-6363(00)00123-1. PubMed PMID: 10963730.

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Shen JZ, Zheng XF, Kwan CY. Differential contractile actions of reactive oxygen species on rat aorta: selective activation of ATP receptor by H2O2. Life Sci. 2000 Apr 14;66(21):PL291-6. doi: 10.1016/s0024-3205(00)00539-7. PubMed PMID: 10823352.

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Shen JZ, Zheng XF. Characteristics of impaired endothelium-dependent relaxation of rat aorta after streptozotocin-induced diabetes. Zhongguo Yao Li Xue Bao. 1999 Sep;20(9):844-50. PubMed PMID: 11245095.

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Shen J, Zheng X. Calcium-activated potassium channel and its regulation invascular smooth muscle cells. Chinese Pharmacological Bulletin. 1998 January; 14(6):488-491.

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Qian S, Shi Y, Peng Q, Senfeld J, Shen J. P2Y2 Receptor Upregulation and Signaling during Adipogenesis and Inflammation: a New Mechanism in Insulin Resistance. EB-2022; 2022 April 2; FESEB.

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Shi Y, Qian S, Alqahtani S, Peng Q, Shen J. CXCR7 Promotes Adipogenesis and Insulin Resistance in Human Visceral Adipocytes. EB-2022; 2022 April 2; FESEB.